We are
working relentlessly to develop innovative and differentiated therapeutics that improve the lives of cancer patients

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Pipeline

Curis is focused on the development and commercialization of innovative therapeutics for the treatment of cancer.

PreclinicalClinicalMarketed
 IndicationProof of PrincipleSafetyDose OptimizationClinical ActivityPivotalCommercial
Heme Malignancies
CA-4948*
IRAK4
MYD88/TLR-altered Lymphoma (NHL)

CA-4948*
IRAK4
IRAK4L-expressing Leukemia (AML/MDS)

Fimepinostat
HDAC/PI3K
MYC-altered Cancers

Immune Checkpoint Inhibitors
CI-8993**
VISTA
VISTA-expressing Cancers

CA-327*
TIM3/PDL1
PDL1/TIM3-expressing Cancers

CA-170*
VISTA/PDL1
PDL1/VISTA-expressing Cancers

Approved Drug
Erivedge***
Hedgehog
Basal Cell Carcinoma

DrugIndicationStage
Heme Malignancies
CA-4948*
IRAK4
MYD88/TLR-altered Lymphoma (NHL)Clinical Activity
CA-4948*
IRAK4
IRAK4L-expressing Leukemia (AML/MDS)Safety
Fimepinostat
HDAC/PI3K
MYC-altered CancersClinical Activity
Immune Checkpoint Inhibitors
CI-8993**
VISTA
VISTA-expressing CancersSafety
CA-327*
TIM3/PDL1
PDL1/TIM3-expressing CancersProof of Principle
CA-170*
VISTA/PDL1
PDL1/VISTA-expressing CancersClinical Activity
Approved Drug
Erivedge***
Hedgehog
Basal Cell CarcinomaCommercial

* IP licensed from Aurigene
** Option to license IP from ImmuNext
*** IP licensed to Genentech (Curis receives royalty income)