We are
working relentlessly to develop innovative and differentiated therapeutics that improve the lives of cancer patients

Spotlight

View our Current Corporate Presentation here.

Curis is focused on the development and commercialization of innovative therapeutics for the treatment of cancer.

	Indication	Proof of Principle	Safety	Commercial
		Preclinical	Clinical	Marketed

Heme Malignancies
Fimepinostat HDAC/PI3K	MYC-altered cancers	FDA Fast Track Designation
CA-4948* IRAK4	MYD88/TLR-altered DLBCL, WM
CA-4948* IRAK4	IL-1R/TLR-altered AML, MDS
Immune Checkpoint Inhibitors
CA-170* VISTA/PDL1	VISTA-expressing Cancers
CI-8993** VISTA	VISTA-expressing Cancers
CA-327* TIM3/PDL1	TIM3-expressing Cancers
Approved Drug
Erivedge*** Hedgehog	Basal Cell Carcinoma

Drug	Indication	Stage
Heme Malignancies
Fimepinostat HDAC/PI3K	MYC-altered cancers	Clinical Activity
CA-4948* IRAK4	MYD88/TLR-altered DLBCL, WM	Dose Optimization
CA-4948* IRAK4	IL-1R/TLR-altered AML, MDS	Proof of Principle
Immune Checkpoint Inhibitors
CA-170* VISTA/PDL1	VISTA-expressing Cancers	Dose Optimization
CI-8993** VISTA	VISTA-expressing Cancers	Proof of Principle
CA-327* TIM3/PDL1	TIM3-expressing Cancers	Proof of Principle
Approved Drug
Erivedge*** Hedgehog	Basal Cell Carcinoma	Commercial

* IP licensed from Aurigene
** IP licensed from ImmuNext
*** IP licensed to Genentech (Curis receives royalty income)